产品货号：
Z14515
中文名称：
FAF1抗体
英文名称：
Anti-FAF1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FAF1 Antibody |
| 指标别名 | CGI 03;FAF1;FAS associated factor 1;hFAF1;HFAF1s;UBXD12;UBXN3A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | FAF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FAF1 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FAF1.The immunogen is located within the last 50 amino acids of FAF1. |
| 计算分子量 | 74kDa |
| 成分 | FAF1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FAF1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Fas-associated protein 1 (FAF1) was initially identified as a Fas-binding pro-apoptotic protein that is component of the death-inducing signaling complex in Fas-mediated apoptosis.FAF1 can also induce apoptosis in the absence of extrinsic death signals when overexpressed although it does not contain typical death motifs such as the death domain,death effector domain,and caspase recruitment domain.Overexpression of FAF1 also decreases the basal level of NF-百B activity in transfected 293 cells,inhibits NF-百B activity induced by TNF-汐，IL-1汕and lipopolysaccharide,and prevents NF-百B translocation to the nucleus,suggesting that another role of FAF1 is to negatively regulate the activity of NF-百B.FAF1 can also interact with the inflammatory signaling PYRIN-containing Apaf-1-like proteins (PYPAFs,also called NALPs) such as PYPAF1,PYPAF2 (NALP2),and PYPAF7,suggesting FAF1 may also be involved in the inflammation pathway.Multiple differentially spliced isoforms of FAF1 are known to exist. |
| Uniprot ID | Q9UNN5 |
| 基因名全称 | Fas (TNFRSF6) associated factor 1 |
| 蛋白名全称 | Fas (TNFRSF6) associated factor 1 |
| 推荐稀释比 | FAF1 antibody can be used for detection of FAF1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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